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Lactase, sucrase, maltase, and palatinase (in lieu of isomaltase) activities can be determined from an intestinal biopsy weighing approximately 5 mg wet weight. The enzyme activities are determined in small bowel biopsies taken via endoscope by the referring clinical physician.
Determination of pancreatic enzyme activities (amylase, chymotrypsin, lipase, and trypsin) in duodenal secretions, usually in conjunction with a secretin stimulation test performed by the referring physician.
Calprotectin is a polyclonal ELISA test designed to determine the amount of Calprotectin in stool samples. It can be utilized to differentiate between inflammatory bowel disease (IBD) and irritable bowl syndrome (IBS) and to monitor treatment for IBD.
Pancreatic elastase (PE) is not degraded during intestinal transit and the concentration of PE in a stool sample reflects exocrine pancreatic function. This assay allows the diagnosis or exclusion of pancreatic exocrine insufficiency, which can be caused by chronic pancreatitis, cystic fibrosis, pancreatic tumor, cholelithiasis or diabetes mellitus.
Non-invasive Helicobacter pylori specific antigen (HpSA) testing can detect an active H. pylori infection in the patient stool specimen. Other antibody tests can screen for H. pylori exposure but cannot distinguish between an active infection and a resolved episode.
Disaccharidase Determination
Pancreatic Elastase (PE) in Stool
Pancreatic Enzyme Determination
Fecal H. Pylori Specific Antigen
Calprotectin